PRODUÇÃO CIENTÍFICA

Aqui, você encontra uma seleção de artigos e estudos acadêmicos.
Navegue pelos links abaixo para conhecer as publicações e descubra como as pesquisas estão contribuindo para o desenvolvimento de novos conhecimentos e práticas na área.

Artigos completos publicados em periódicos

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Orientações e supervisões concluídas

2025

Atividade antibacteriana dos canabinoides sobre a bactéria causadora da tuberculose: uma revisão sistemática

SOUZA, G. A. S. C. ; ANDRADE, R. L. P. ; DOS SANTOS, R. G. ; ROSSI, G. N. ; CHAVES, F. N. R. ; HALLAK, JAIME E. ; ORFAO, N. H.

Revista Brasileira de Análises Clínicas 2025
Adverse Effects and Safety of Antidepressants and Psychedelics for Depression in Cancer: A Systematic Review of Randomized Controlled Trials

MAEKAWA, R. M., GUERRA, L. T. L., BOUSO, J. C., HALLAK, J. E., DOS SANTOS, R. G.

Psychoactives 2025
Ayahuasca, Pain, and Inflammation: A Systematic Review of Preclinical Studies

VILLANOVA, B. ; ROSSI, G. N. ; GUERRA, L. T. L. ; BOUSO, JOSÉ C ; HALLAK, J. E. C. ; DOS SANTOS, R.G

Psychoactives 2025
The Ibogaine Experience Scale (IES): Development and psychometric properties of a multidimensional measure of ibogaine’s subjective effects

ESPEJITO, F. G., RODRIGUEZ, L. E., PEREZ, E. J. P., DICKINSON, J., KOHEK, M., DOS SANTOS, R. G., HALLAK, J. E. C., ALCÁZAR, M. A., BOUSO, J. C.

PLoS One 2025
Clinical pharmacology of ayahuasca: potential applications and future considerations

GUERRA, L. T. L., DIAS, I. C. S., HALLAK, J. E. C., DOS SANTOS, R. G.

Expert Review of Clinical Pharmacology 2025
Psychedelic-induced behavioral and developmental effects on zebrafish: a systematic review

DE OLIVEIRA, A. L., DE OLIVEIRA, D. P., DOS SANTOS, R. G., HALLAK, J. E.

Progress in Neuro-Psychopharmacology and Biological Psychiatry 2025
Adverse Effects and Safety of Antidepressants and Psychedelics for Depression in Cancer: A Systematic Review of Randomized Controlled Trials

MAEKAWA, R. M.; GUERRA, L. T. L.; BOUSO, J. C.; HALLAK, J. E. C.; SANTOS, R. G.

Psychoactives 2025

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Atividade antibacteriana dos canabinoides sobre a bactéria causadora da tuberculose: uma revisão sistemática

Adverse Effects and Safety of Antidepressants and Psychedelics for Depression in Cancer: A Systematic Review of Randomized Controlled Trials

Ayahuasca, Pain, and Inflammation: A Systematic Review of Preclinical Studies

The Ibogaine Experience Scale (IES): Development and psychometric properties of a multidimensional measure of ibogaine’s subjective effects

Clinical pharmacology of ayahuasca: potential applications and future considerations

Psychedelic-induced behavioral and developmental effects on zebrafish: a systematic review

Adverse Effects and Safety of Antidepressants and Psychedelics for Depression in Cancer: A Systematic Review of Randomized Controlled Trials

Why N,N-dimethyltryptamine matters: unique features and therapeutic potential beyond classical psychedelics.

Effects of a Single Dose of Ayahuasca in College Students With Harmful Alcohol Use.

Ayahuasca¿enhanced extinction of fear behaviour: Role of infralimbic cortex 5¿HT 2A and 5¿HT 1A receptors.

Ketamine-induced altered states of consciousness: a systematic review of implications for therapeutic outcomes in psychiatric practices.

Effects of ayahuasca on fear and anxiety: cross-talk between 5HT1A and 5HT2A receptors.

Ayahuasca: pharmacology, safety, and therapeutic effects.

Long-term ayahuasca use is associated with preserved global cognitive function and improved memory: a cross-sectional study with ritual users.

Lack of Acute Agomelatine Effect in a Model of Social Anxiety in Healthy Volunteers A Double-Blind, Placebo-Controlled Trial.

Solvent-free parallel artificial liquid membrane extraction for drugs of abuse in plasma samples using LC-MS/MS.

Ayahuasca-enhanced extinction of fear behaviour: Role of infralimbic cortex 5-HT2A and 5-HT1A receptors.

The effects of ketamine and classic hallucinogens on neurotrophic and inflammatory markers in unipolar treatment-resistant depression: a systematic review of clinical trials.

Subjective Effects of a Single Dose of Ayahuasca among College Students with Harmful Alcohol Use: Qualitative Analysis of Participant Accounts.

Longitudinal and transcultural assessment of the relationship between hallucinogens, well-being, and post-traumatic growth during the COVID-19 pandemic. Scientific Reports.

Interventions for Deficits in Recognition of Emotions in Facial Expressions in Major Depressive Disorder: An Updated Systematic Review of Clinical Trials.

Interventions for deficits in recognition of emotions in facial expressions in major depressive disorder: An updated systematic review of clinical trials.

Biases in affective attention tasks in posttraumatic stress disorder patients: A systematic review of neuroimaging studies.

Current Evidence of Cannabidiol's Potential as an Anxiolytic Agent.

Multifaceted Empathy Test (MET): Validity evidence for the Brazilian population concerning the computer-based (face-to-face) and online versions.

Neural Network Modulation of Ayahuasca: A Systematic Review of Human Studies.

Identifying setting factors associated with improved ibogaine safety: A systematic review of clinical studies.

Hallucinations and Hallucinogens: Psychopathology or Wisdom?

Adverse Effects of Oral Cannabidiol: An Updated Systematic Review of Randomized Controlled Trials (2020–2022).

Natural Hallucinogens in Mental Health. Psychoactives.

Underground ibogaine use for the treatment of substance use disorders: A qualitative analysis of subjective experiences.

Molecular level pathways of the therapeutic effects of ayahuasca, a botanical hallucinogen and potential rapid-acting antidepressant.

Tripping to Cope: Coping Strategies and Use of Hallucinogens during the COVID-19 Pandemic in Three Cultural Contexts.

Maintained anxiolytic effects of cannabidiol after treatment discontinuation in healthcare workers during the COVID-19 pandemic.

Safety issues of psilocybin and LSD as potential rapid acting antidepressants and potential challenges.

Ayahuasca, a potentially rapid acting antidepressant: focus on safety and tolerability.

Ayahuasca, a potentially rapid acting antidepressant: focus on safety and tolerability.

Effects of ayahuasca on the endocannabinoid system of healthy volunteers and in volunteers with social anxiety disorder: Results from two pilot, proof-of-concept, randomized, placebo-controlled trials

Adverse Effects After Ayahuasca Administration in the Clinical Setting.

Avaluació de l?estat de salut, els patrons de consum i els beneficis subjectius del cànnabis medicinal en una mostra de pacients catalans amb malalties cròniques.

Cannabidiol for COVID-19 Patients with Mild to Moderate Symptoms (CANDIDATE Study): A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

The Adverse Events of Ibogaine in Humans: An Updated Systematic Review of the Literature (2015-2020).

Effects of Ayahuasca on Personality: Results of Two Randomized, Placebo-Controlled Trials in Healthy Volunteers.

ross-Sectional Associations Between Lifetime Use of Psychedelic Drugs and Psychometric Measures During the COVID-19 Confinement: A Transcultural Study.

Efficacy and Safety of Cannabidiol Plus Standard Care vs Standard Care Alone for the Treatment of Emotional Exhaustion and Burnout Among Frontline Health Care Workers During the COVID-19 Pandemic.

Effects of ayahuasca and its alkaloids on substance use disorders: an updated (2016-2020) systematic review of preclinical and human studies.

Ayahuasca Improves Self-perception of Speech Performance in Subjects With Social Anxiety Disorder.

The Use of Classic Hallucinogens/Psychedelics in a Therapeutic Context: Healthcare Policy Opportunities and Challenges.

ffects of Ayahuasca on the Recognition of Facial Expressions of Emotions in Naive Healthy Volunteer.

Acute Psychological Adverse Reactions in First-Time Ritual Ayahuasca Users A Prospective Case Series.

Hallucinogenic/psychedelic 5HT2A receptor agonists as rapid antidepressant therapeutics: Evidence and mechanisms of action.

Ayahuasca, an ancient substance with traditional and contemporary use in neuropsychiatry and neuroscience.

Ayahuasca and Public Health II: Health Status in a Large Sample of Ayahuasca-Ceremony Participants in the Netherlands.

Essential oil-based dispersive liquid-liquid microextraction for the determination of N,N-dimethyltryptamine and β-carbolines in human plasma: a novel solvent-free alternative.

Rapid and sustained decreases in suicidality following a single dose of ayahuasca among individuals with recurrent major depressive disorder: results from an open-label trial.

Rapid and sustained decreases in suicidality following a single dose of ayahuasca among individuals with recurrent major depressive disorder: results from an open-label trial.

Polypharmacology or ¿Pharmacological Promiscuity¿ In Psychedelic Research: What Are We Missing?

Unveiling ayahuasca psychopharmacology: the accomplishments of Jordi Riba (1968-2020).

Cross-cultural adaptation of the City Birth Trauma Scale for the Brazilian context.

The effects of Cannabidiol (CBD) and Delta-9-Tetrahydrocannabinol (THC) on the recognition of emotions in facial expressions: A systematic review of randomized controlled trials.

Risk assessment of ayahuasca use in a religious context: self-reported risk factors and adverse effects.

Stability evaluation of DMT and harmala alkaloids in ayahuasca tea samples.

Hallucinogens/psychedelics resurrected as new tools in psychiatric therapy.

Serious adverse effects of cannabidiol (CBD): a review of randomized controlled trials.

Effects of ayahuasca on mental health and quality of life in naïve users: A longitudinal and cross-sectional study combination.

Quality of Life, Mental Health, Personality and Patterns of Use in Self-Medicated Cannabis Users with Chronic Diseases: A 12-Month Longitudinal Study

ross-cultural adaptation of the Internet Gaming Disorder Scale - Short Form (IGDS9-SF) to the Brazilian context.

Therapeutic use of serotoninergic hallucinogens: a review of the evidence and of the biological and psychological mechanisms.

Modulation of the Endocannabinoid and Oxytocinergic Systems as a Potential Treatment Approach for Social Anxiety Disorder.

Serotonergic hallucinogens/psychedelics could be promising treatments for depressive and anxiety disorders in end-stage cancer.

Clinical validity and intrarater and test-retest reliability of the Structured Clinical Interview for DSM-5 Disorders-Clinician Version (SCID-5-CV).

Translational evidence for ayahuasca as an antidepressant: what’s next?

An analytical study of iboga alkaloids contained in Tabernanthe iboga-derived products offered by ibogaine treatment providers.

Serotonergic hallucinogens and recognition of facial emotion expressions: a systematic review of the literature.

O uso do canabidiol (CBD) no tratamento da doença de Parkinson e suas comorbidades.

Internet method for the extraction of N,N -dimethyltryptamine from Mimosa hostilis roots: Does it really extract dimethyltryptamine?

Is cannabidiol the ideal drug to treat non-motor Parkinson?s disease symptoms?

Personality Inventory for DSM-5 (PID-5): cross-cultural adaptation and content validity in the Brazilian context.

Ayahuasca and Public Health: Health Status, Psychosocial Well-Being, Lifestyle, and Coping Strategies in a Large Sample of Ritual Ayahuasca Users.

Efficacy, tolerability, and safety of serotonergic psychedelics for the management of mood, anxiety and substance use disorders: a systematic review of systematic reviews.